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SS-31 (Elamipretide)

Mitochondrial Optimizer

A breakthrough peptide that targets mitochondria directly. Enhances cellular energy production and supports healthy aging.

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Key Benefits

Mitochondrial Function

Targets and optimizes mitochondria, the powerhouses of your cells, improving energy production.

Cellular Energy (ATP)

Increases ATP production, giving you more energy at the cellular level for all bodily functions.

Oxidative Stress Reduction

Protects mitochondria from damage caused by reactive oxygen species (ROS).

Cardiovascular Support

Shows promise for heart health by supporting cardiac muscle energy production.

How SS-31 Works

SS-31 is unique among peptides because it specifically targets mitochondria—the organelles responsible for producing 90% of your body's cellular energy. Unlike other supplements that work indirectly, SS-31 accumulates directly in mitochondria due to its special chemical structure.

The Mitochondrial Problem

As we age, mitochondrial function declines. This leads to:

  • Decreased energy production (ATP)
  • Increased oxidative stress and cellular damage
  • Reduced capacity for tissue repair
  • Accelerated aging across all organ systems

The SS-31 Solution

SS-31 works by:

  • Stabilizing cardiolipin: This phospholipid is critical for mitochondrial membrane integrity. SS-31 prevents its oxidation and maintains optimal function.
  • Improving electron transport: By stabilizing the inner membrane, SS-31 enhances the efficiency of ATP production.
  • Reducing ROS: It decreases the production of harmful reactive oxygen species that damage cellular components.
  • Supporting cell survival: SS-31 helps prevent apoptosis (cell death) triggered by mitochondrial dysfunction.

Research Highlights

"Improved mitochondrial function and reduced oxidative stress in aging models"

— Journal of the American Heart Association

"Enhanced exercise capacity and reduced fatigue in clinical trials"

— Circulation: Heart Failure

"Protected cardiac tissue during ischemia-reperfusion injury"

— Journal of Molecular and Cellular Cardiology

"Improved skeletal muscle function in age-related decline"

— Aging Cell

Note: SS-31 is currently in clinical trials and is not FDA-approved. Research findings represent ongoing scientific investigation.

Frequently Asked Questions

What is SS-31 (Elamipretide)?
SS-31, also known as Elamipretide or Bendavia, is a synthetic tetrapeptide that specifically targets mitochondria. It was developed to treat mitochondrial dysfunction, which is implicated in aging and many age-related diseases.
How does SS-31 work?
SS-31 concentrates in the inner mitochondrial membrane where it stabilizes cardiolipin, a key phospholipid essential for mitochondrial function. This stabilization improves electron transport chain efficiency and ATP production while reducing harmful ROS.
Who might benefit from SS-31?
SS-31 may benefit individuals experiencing age-related fatigue, those looking to optimize cellular energy, athletes seeking recovery support, and people interested in longevity and healthy aging protocols.
What conditions is SS-31 being researched for?
SS-31 is being studied for heart failure (Barth syndrome), primary mitochondrial myopathy, age-related macular degeneration, and general age-related mitochondrial dysfunction.
When will SS-31 be available at MetabolixPH?
We're working to bring SS-31 to our platform in 2025. Join our waitlist to be notified when it becomes available.

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