Ozempic Semaglutide GLP-1 Weight Loss

Why We Don't Prescribe Ozempic (And What We Recommend Instead)

Learn why MetabolixPH doesn't offer Semaglutide (Ozempic) and why we believe Tirzepatide and Retatrutide are better options for weight loss.

MetabolixPH Team ·

Ozempic has become synonymous with weight loss, thanks to celebrity endorsements and social media buzz. So why doesn’t MetabolixPH offer it? The answer isn’t about availability—it’s about offering you the best possible results.

The Short Answer

We don’t offer Semaglutide (Ozempic/Wegovy) because newer medications—Tirzepatide and Retatrutide—are simply more effective. When you’re investing in weight loss treatment, we believe you deserve the best outcomes science can offer.

Understanding Semaglutide (Ozempic)

What It Is

Semaglutide is a GLP-1 receptor agonist developed by Novo Nordisk. It’s sold under two main brand names:

  • Ozempic — Approved for Type 2 diabetes
  • Wegovy — Same drug, higher dose, approved for weight loss

How It Works

Semaglutide activates one receptor:

  • GLP-1 — Reduces appetite, slows gastric emptying, improves blood sugar control

Its Track Record

Semaglutide was groundbreaking when it launched. The STEP clinical trials showed:

  • Average weight loss of 12-15% body weight
  • Significant improvements in metabolic health
  • Generally well-tolerated

For years, it was the most effective weight loss medication available. But science moves forward.

Why We Chose Tirzepatide and Retatrutide Instead

Tirzepatide: The Upgrade

Tirzepatide (Mounjaro/Zepbound) came after Semaglutide with an important improvement—it activates TWO receptors instead of one:

  • GLP-1 — Same as Semaglutide
  • GIP — Additional pathway for insulin sensitivity and fat metabolism

The result: 15-21% average weight loss vs. 12-15% for Semaglutide

Retatrutide: The Next Level

Retatrutide goes even further with THREE receptors:

  • GLP-1 — Appetite suppression
  • GIP — Metabolic enhancement
  • Glucagon — Increased energy expenditure

The result: 17-24% average weight loss

Head-to-Head Comparison

MetricSemaglutideTirzepatideRetatrutide
Receptors123
Avg. Weight Loss12-15%15-21%17-24%
Generation1st2nd3rd
MechanismSingleDualTriple

What This Means in Real Numbers

For someone weighing 90kg:

MedicationExpected LossFinal Weight
Semaglutide~12kg~78kg
Tirzepatide~17kg~73kg
Retatrutide~20kg~70kg

That’s an 8kg difference between Semaglutide and Retatrutide—a significant amount that could mean reaching your goal weight versus falling short.

The “Ozempic Face” Problem

You may have heard of “Ozempic face”—the gaunt, aged appearance some people develop after significant weight loss on GLP-1 medications. This happens because:

  1. Rapid weight loss can cause facial fat loss
  2. Single-mechanism drugs like Semaglutide don’t protect muscle mass as well
  3. The weight lost includes both fat and lean tissue

Why Retatrutide may be better: The glucagon component helps preserve lean muscle mass while promoting fat loss. Early data suggests better body composition outcomes—meaning you lose fat, not muscle.

Popularity doesn’t equal effectiveness. Ozempic’s fame comes from:

Marketing Momentum

Novo Nordisk has spent billions marketing Ozempic. It was first to market with massive clinical trials, creating strong brand recognition.

Celebrity Endorsements

When celebrities and influencers mention weight loss injections, they usually say “Ozempic” even if they’re using something else. It’s become a generic term like “Xerox” for photocopies.

Name Recognition

Doctors who aren’t specialists in weight loss often prescribe what they know—and they know Ozempic.

Insurance Coverage

In some countries, Ozempic has better insurance coverage because it’s been around longer. This isn’t a factor in the Philippines where most patients pay out-of-pocket anyway.

What About Cost?

Some might argue Semaglutide is cheaper. Let’s examine:

Raw Price Comparison

MedicationMetabolixPH Starting Price
SemaglutideNot offered
Tirzepatide₱4,500/month
Retatrutide₱6,500/month

Cost Per Kilogram Lost

Here’s where it gets interesting. If we calculate cost-effectiveness:

Tirzepatide:

  • Cost: ₱4,500/month × 6 months = ₱27,000
  • Weight loss: ~17kg
  • Cost per kg: ~₱1,588

Comparable Semaglutide (if offered):

  • Would cost: ~₱4,000/month × 6 months = ₱24,000
  • Weight loss: ~12kg
  • Cost per kg: ~₱2,000

Even though Semaglutide has a lower monthly cost, you’d pay MORE per kilogram lost because it’s less effective.

When Semaglutide Might Make Sense

To be fair, there are scenarios where Semaglutide could be appropriate:

  1. You can’t tolerate Tirzepatide — Some patients do better on single-agonist medications
  2. Your doctor specifically recommends it — For diabetes management, not weight loss
  3. You’ve had success with it before — If it worked, why change?
  4. It’s covered by your insurance — Relevant for international patients

But for most people seeking weight loss in the Philippines? Tirzepatide and Retatrutide are better options.

Our Philosophy: Better Results, Fair Prices

At MetabolixPH, our goal isn’t to offer every medication on the market. It’s to offer the most effective treatments at accessible prices.

Adding Semaglutide would:

  • Dilute our focus
  • Give patients an inferior option
  • Require us to explain why it’s not the best choice

Instead, we’d rather:

  • Specialize in the best available treatments
  • Help patients achieve better results
  • Be honest about what works best

Frequently Asked Questions

I’m already on Ozempic. Should I switch?

If you’re happy with your results, there’s no urgent need to switch. However, if you’ve plateaued or want to accelerate your weight loss, Tirzepatide or Retatrutide could help you reach the next level.

My doctor prescribed Ozempic. Is that wrong?

Not necessarily. For diabetes management, Ozempic is excellent. For weight loss, there are now better options. You might ask your doctor about Tirzepatide if weight loss is your primary goal.

Is Ozempic dangerous?

No. Ozempic is FDA-approved and has an excellent safety record. Our point isn’t that Ozempic is bad—it’s that newer options are better for weight loss.

Will you ever offer Semaglutide?

Unlikely, unless clinical evidence changes significantly. We prefer to focus on the most effective treatments rather than offering every option.

What if Tirzepatide/Retatrutide don’t work for me?

Individual responses vary. If our recommended treatments don’t work well for you, we’d help you explore why and potentially refer you to a specialist for alternative approaches.

The Bottom Line

Ozempic was revolutionary when it launched. It proved that GLP-1 medications could achieve meaningful weight loss. But science has progressed, and we now have more effective options.

At MetabolixPH, we offer:

Tirzepatide — For those seeking a proven, cost-effective dual-agonist treatment

Retatrutide — For those wanting maximum results with the most advanced triple-agonist technology

Both outperform Semaglutide in clinical trials. Both are available at fair prices. And both represent our commitment to offering the best, not just the most popular.


Ready to try a more effective approach? Take our quiz to see which treatment is right for you.

Ready to Start Your Weight Loss Journey?

Take our 2-minute quiz for a personalized treatment recommendation.

Find Your Treatment →
M

MetabolixPH Team

The MetabolixPH team includes healthcare professionals and medical writers dedicated to providing accurate, up-to-date information about weight loss treatments.