Retatrutide in the Philippines: Complete 2025 Guide
Everything you need to know about Retatrutide in the Philippines - how it works, expected results, pricing, and how to get it legally through MetabolixPH.
Retatrutide is the most advanced weight loss medication ever developed, and it’s now available in the Philippines exclusively through MetabolixPH. In this comprehensive guide, we’ll cover everything you need to know about this groundbreaking treatment.
What is Retatrutide?
Retatrutide is a next-generation weight loss medication developed by Eli Lilly. Unlike earlier GLP-1 medications, Retatrutide is a triple agonist — meaning it activates three different hormone receptors:
- GLP-1 (Glucagon-like peptide-1) — Reduces appetite and slows stomach emptying
- GIP (Glucose-dependent insulinotropic polypeptide) — Enhances insulin sensitivity and fat metabolism
- Glucagon — Increases energy expenditure and promotes fat burning
This triple mechanism makes Retatrutide potentially the most effective weight loss medication available anywhere in the world.
Clinical Trial Results
The results from Retatrutide clinical trials have been remarkable:
| Dose | Average Weight Loss | Trial Duration |
|---|---|---|
| 4mg | 17.5% body weight | 48 weeks |
| 8mg | 22.1% body weight | 48 weeks |
| 12mg | 24.2% body weight | 48 weeks |
To put this in perspective, if you weigh 90kg:
- At the 4mg dose, you could expect to lose around 15.7kg
- At the 12mg dose, you could expect to lose around 21.8kg
These results surpass all other weight loss medications currently available, including Tirzepatide (Mounjaro/Zepbound) and Semaglutide (Ozempic/Wegovy).
How Does Retatrutide Work?
Retatrutide works through multiple complementary mechanisms:
Appetite Suppression
Like other GLP-1 medications, Retatrutide significantly reduces hunger. Most patients report feeling satisfied with smaller portions and experiencing fewer cravings between meals.
Slowed Gastric Emptying
Food stays in your stomach longer, which means you feel full for extended periods after eating. This naturally leads to reduced calorie intake without the need for strict dieting.
Increased Energy Expenditure
The glucagon component is what sets Retatrutide apart. Glucagon activation increases your body’s energy expenditure, meaning you burn more calories even at rest. This is a significant advantage over dual-agonist medications.
Improved Metabolic Health
Beyond weight loss, Retatrutide has shown benefits for:
- Blood sugar control
- Cholesterol levels
- Blood pressure
- Liver fat reduction
Who is Retatrutide For?
Retatrutide may be appropriate for adults who:
- Have a BMI of 27 or higher (using Asian BMI cutoffs)
- Have struggled with weight loss through diet and exercise alone
- Want to achieve significant, sustained weight loss
- Are looking for the most effective available treatment
Who Should NOT Take Retatrutide
Retatrutide is not suitable for everyone. You should not take Retatrutide if you have:
- Type 1 diabetes
- Personal or family history of medullary thyroid cancer
- Multiple endocrine neoplasia syndrome type 2 (MEN 2)
- History of pancreatitis
- Are pregnant or breastfeeding
Retatrutide Dosing Schedule
Retatrutide is administered once weekly via subcutaneous injection. The typical titration schedule is:
| Week | Dose |
|---|---|
| 1-4 | 2mg |
| 5-8 | 4mg |
| 9-12 | 8mg |
| 13+ | 12mg (maintenance) |
Your physician may adjust this schedule based on your response and tolerability.
Side Effects
Like all GLP-1 medications, Retatrutide can cause side effects. The most common include:
Gastrointestinal (most common):
- Nausea (usually temporary)
- Diarrhea
- Constipation
- Vomiting
Other possible side effects:
- Injection site reactions
- Fatigue
- Dizziness
Most side effects are mild to moderate and tend to decrease as your body adjusts to the medication. Starting at a lower dose and titrating slowly helps minimize these effects.
Retatrutide Pricing in the Philippines
At MetabolixPH, we offer Retatrutide at the following prices:
| Dose | Price per Month |
|---|---|
| 2mg | ₱6,500 |
| 4mg | ₱9,500 |
| 8mg | ₱14,500 |
| 12mg | ₱18,500 |
Each order includes:
- 4-week supply (4 doses)
- Physician review
- Injection supplies
- Free nationwide delivery
How to Get Retatrutide in the Philippines
MetabolixPH is currently the only platform offering Retatrutide in the Philippines. Here’s how to get started:
- Take our quiz — Answer questions about your health goals and medical history
- Physician review — A licensed Philippine physician reviews your information
- Prescription issued — If approved, you’ll receive a prescription
- Delivery — Your medication arrives in discreet packaging within 3-5 days
Retatrutide vs. Other Weight Loss Medications
| Medication | Mechanism | Avg. Weight Loss | Availability |
|---|---|---|---|
| Retatrutide | Triple (GLP-1 + GIP + Glucagon) | 17-24% | MetabolixPH only |
| Tirzepatide | Dual (GLP-1 + GIP) | 15-21% | Multiple providers |
| Semaglutide | Single (GLP-1) | 12-15% | Multiple providers |
Frequently Asked Questions
Is Retatrutide FDA-approved?
Retatrutide is currently in Phase 3 clinical trials and is expected to receive FDA approval in 2025. At MetabolixPH, we offer compounded Retatrutide from FDA-registered facilities.
How long until I see results?
Most patients notice reduced appetite within the first week. Significant weight loss typically becomes noticeable within 4-8 weeks.
Do I need to diet while taking Retatrutide?
While Retatrutide doesn’t require strict dieting, you’ll achieve better results by making healthy food choices. The medication makes this easier by reducing cravings and appetite.
Can I take Retatrutide with other medications?
Retatrutide can interact with certain medications, particularly diabetes medications. Our physicians will review your complete medication list before prescribing.
What happens if I stop taking Retatrutide?
Some weight regain is possible after stopping any weight loss medication. Many patients choose to continue at a maintenance dose long-term.
The Bottom Line
Retatrutide represents a significant advancement in weight loss treatment. With its triple mechanism of action, it offers the potential for greater weight loss than any other available medication.
If you’ve struggled with weight loss and are looking for an effective, physician-guided solution, Retatrutide may be right for you.
Ready to learn more? Take our 2-minute quiz to see if Retatrutide is appropriate for your goals.
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Find Your Treatment →MetabolixPH Team
The MetabolixPH team includes healthcare professionals and medical writers dedicated to providing accurate, up-to-date information about weight loss treatments.